Benzenemethanamine, 3,4-dichloro- → HCID 59392910, compound

HRID 536122Notes

Reaction equation

HRID 536122 reaction equation
C[O:2][C:3]([C:5]1[N:6]=[C:7]2[CH:16]=[CH:15][C:14]([N:17]3[CH2:22][CH2:21][CH2:20][CH2:19][CH2:18]3)=[CH:13][N:8]2[C:9](=[O:12])[C:10]=1[OH:11])=O.[Cl:23][C:24]1[CH:25]=[C:26]([CH:29]=[CH:30][C:31]=1[Cl:32])[CH2:27][NH2:28]>>[Cl:23][C:24]1[CH:25]=[C:26]([CH:29]=[CH:30][C:31]=1[Cl:32])[CH2:27][NH:28][C:3]([C:5]1[N:6]=[C:7]2[CH:16]=[CH:15][C:14]([N:17]3[CH2:18][CH2:19][CH2:20][CH2:21][CH2:22]3)=[CH:13][N:8]2[C:9](=[O:12])[C:10]=1[OH:11])=[O:2]

Participants

3

Reactant 2

HCID 1608Benzenemethanamine, 3,4-dichloro-HCID 58101059HCID 58101059, compound

Product 1

HCID 59392910HCID 59392910, compound

Procedure

Using the product of Example 2.6, the procedure described in Example 6 was adapted (except only 1.3 eq. of 3,4-dichlorobenzylamine was used) to afford the desired compound.

Sources & evidence

ORD record
ord-768ca899e01d47dbae58c99ba5d76aca
Source dataset
uspto-grants-2014_10
Patent number
US08859563B2

Reaction notes

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