4-Fluorobenzaldehyde → 4-(4-Chloro-3-(trifluoromethyl)phenoxy)benzaldehyde

HRID 536153Notes

Reaction equation

HRID 536153 reaction equation
F[C:2]1[CH:9]=[CH:8][C:5]([CH:6]=[O:7])=[CH:4][CH:3]=1.[Cl:10][C:11]1[CH:16]=[CH:15][C:14]([OH:17])=[CH:13][C:12]=1[C:18]([F:21])([F:20])[F:19]>>[Cl:10][C:11]1[CH:16]=[CH:15][C:14]([O:17][C:2]2[CH:9]=[CH:8][C:5]([CH:6]=[O:7])=[CH:4][CH:3]=2)=[CH:13][C:12]=1[C:18]([F:19])([F:20])[F:21]

Participants

3

Reactant 2

HCID 680234-FluorobenzaldehydeHCID 805204-Chloro-3-(trifluoromethyl)phenol

Product 1

HCID 866661874-(4-Chloro-3-(trifluoromethyl)phenoxy)benzaldehyde

Procedure

The title compound was prepared by a procedure similar to that described for D1 starting from 4-fluorobenzaldehyde and 4-Chloro-3-(trifluoromethyl)phenol. LC-MS (ESI): m/z 301 [M+H]+; 3.76 min (ret time).

Workup

  1. custom3.76 min (ret time)

Sources & evidence

ORD record
ord-ff163dce47164761869b16d4c2d24652
Source dataset
uspto-grants-2014_10
Patent number
US08859573B2

Reaction notes

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