4-Chloro-3-(trifluoromethyl)phenol → HCID 66826128, compound

HRID 536157Notes

Reaction equation

HRID 536157 reaction equation
F[C:2]1[CH:3]=[CH:4][C:5]([C:8]#[N:9])=[N:6][CH:7]=1.[Cl:10][C:11]1[CH:16]=[CH:15][C:14]([OH:17])=[CH:13][C:12]=1[C:18]([F:21])([F:20])[F:19]>>[Cl:10][C:11]1[CH:16]=[CH:15][C:14]([O:17][C:2]2[CH:3]=[CH:4][C:5]([C:8]#[N:9])=[N:6][CH:7]=2)=[CH:13][C:12]=1[C:18]([F:19])([F:20])[F:21]

Participants

3

Reactant 2

HCID 805204-Chloro-3-(trifluoromethyl)phenolHCID 113324532-Cyano-5-fluoropyridine

Product 1

HCID 66826128HCID 66826128, compound

Procedure

The title compound was prepared by a procedure similar to that described for D1 starting from 5-fluoro-2-pyridinecarbonitrile and 4-chloro-3-(trifluoromethyl)phenol. LC-MS (ESI): m/z 299 [M+H]+; 3.59 min (ret time).

Workup

  1. custom3.59 min (ret time)

Sources & evidence

ORD record
ord-9ccbaadd2b024d82ab3e8d104516f49d
Source dataset
uspto-grants-2014_10
Patent number
US08859573B2

Reaction notes

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