3-(Trifluoromethyl)phenol → Benzonitrile, 5-formyl-2-[3-(trifluoromethyl)phenoxy]-

HRID 536163Notes

Reaction equation

HRID 536163 reaction equation
[F:1][C:2]([F:11])([F:10])[C:3]1[CH:4]=[C:5]([OH:9])[CH:6]=[CH:7][CH:8]=1.F[C:13]1[CH:20]=[CH:19][C:18]([CH:21]=[O:22])=[CH:17][C:14]=1[C:15]#[N:16]>>[CH:21]([C:18]1[CH:19]=[CH:20][C:13]([O:9][C:5]2[CH:6]=[CH:7][CH:8]=[C:3]([C:2]([F:10])([F:11])[F:1])[CH:4]=2)=[C:14]([CH:17]=1)[C:15]#[N:16])=[O:22]

Participants

3

Reactant 2

HCID 73763-(Trifluoromethyl)phenolHCID 27695822-Fluoro-5-formylbenzonitrile

Product 1

HCID 86666203Benzonitrile, 5-formyl-2-[3-(trifluoromethyl)phenoxy]-

Procedure

The title compound was prepared by a procedure similar to that described for D starting from 3-Trifluoromethyl-phenol and 2-Fluoro-5-formyl-benzonitrile.

Sources & evidence

ORD record
ord-d963f7baeeca45568b5c7fbb90517e02
Source dataset
uspto-grants-2014_10
Patent number
US08859573B2

Reaction notes

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