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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 536167Generated: October 26, 2026

4-Chloro-3-(trifluoromethyl)phenol → 6-{[4-Chloro-3-(trifluoromethyl)phenyl]oxy}-5-fluoro-3-pyridinecarbaldehyde

https://huagongshe.com/reaction/536167

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chloro-3-(trifluoromethyl)phenolHCID 80520—
Reactant6-Chloro-5-fluoropyridine-3-carbaldehydeHCID 21698194—
Product6-{[4-Chloro-3-(trifluoromethyl)phenyl]oxy}-5-fluoro-3-pyridinecarbaldehydeHCID 86689894—

Reaction Steps

The title compound was prepared by a procedure similar to that described for D1 starting from 6-chloro-5-fluoro-3-pyridinecarbaldehyde and 4-chloro-3-(trifluoromethyl)phenol. LC-MS (ESI): m/z 320 [M+H]+; 3.62 min (ret time).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08859573B2
Source datasetuspto-grants-2014_10
ORD IDord-51ff212c60cb440da0fa9997de19d953
Source noteuspto-grants-2014_10