Tyrosol → HCID 67958437, compound

HRID 536176Notes

Reaction equation

HRID 536176 reaction equation
[OH:1][CH2:2][CH2:3][C:4]1[CH:9]=[CH:8][C:7]([OH:10])=[CH:6][CH:5]=1.Cl[C:12]1[N:17]=[C:16]([C:18]([F:21])([F:20])[F:19])[CH:15]=[CH:14][N:13]=1>>[F:19][C:18]([F:21])([F:20])[C:16]1[CH:15]=[CH:14][N:13]=[C:12]([O:10][C:7]2[CH:8]=[CH:9][C:4]([CH2:3][CH2:2][OH:1])=[CH:5][CH:6]=2)[N:17]=1

Participants

3

Reactant 2

HCID 10393TyrosolHCID 27739122-Chloro-4-(trifluoromethyl)pyrimidine

Product 1

HCID 67958437HCID 67958437, compound

Procedure

The title compound was prepared by a procedure similar to that described for D1 starting from 4-(2-hydroxyethyl)phenol and 2-chloro-4-(trifluoromethyl)pyrimidine. LC-MS (ESI): m/z 285 [M+H]+; 2.66 min (ret time).

Workup

  1. custom2.66 min (ret time)

Sources & evidence

ORD record
ord-8114c97ea1954e53a5a0f71dcec7e12c
Source dataset
uspto-grants-2014_10
Patent number
US08859573B2

Reaction notes

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