2-Chloro-5-(trifluoromethyl)pyridine → HCID 86697029, compound

HRID 536179Notes

Reaction equation

HRID 536179 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[OH:10])[CH:5]=[O:6].Cl[C:12]1[CH:17]=[CH:16][C:15]([C:18]([F:21])([F:20])[F:19])=[CH:14][N:13]=1>>[F:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[O:10][C:12]1[CH:17]=[CH:16][C:15]([C:18]([F:21])([F:20])[F:19])=[CH:14][N:13]=1)[CH:5]=[O:6]

Participants

3

Reactant 2

HCID 923422-Chloro-5-(trifluoromethyl)pyridineHCID 5872503-Fluoro-4-hydroxybenzaldehyde

Product 1

HCID 86697029HCID 86697029, compound

Procedure

The title compound was prepared by a procedure similar to that described for D1 starting from 3-fluoro-4-hydroxybenzaldehyde and 2-chloro-5-(trifluoromethyl)pyridine, LC-MS (ESI): m/z 286 [M+H]+; 3.37 min (ret time).

Workup

  1. custom3.37 min (ret time)

Sources & evidence

ORD record
ord-3842d711df5a4da79e524f6ae0b803f5
Source dataset
uspto-grants-2014_10
Patent number
US08859573B2

Reaction notes

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