HCID 21698362, compound → HCID 57383265, compound

HRID 536199Notes

Reaction equation

HRID 536199 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][C:9]2[CH:14]=[CH:13][C:12]([CH2:15][CH2:16][O:17][C:18]3[CH:23]=[CH:22][NH:21][C:20](=[O:24])[CH:19]=3)=[CH:11][CH:10]=2)=[CH:4][C:3]=1[C:25]([F:28])([F:27])[F:26].Cl[CH2:30][C:31]1[CH:32]=[N:33][N:34]([CH3:36])[CH:35]=1>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][C:9]2[CH:10]=[CH:11][C:12]([CH2:15][CH2:16][O:17][C:18]3[CH:23]=[CH:22][N:21]([CH2:30][C:31]4[CH:32]=[N:33][N:34]([CH3:36])[CH:35]=4)[C:20](=[O:24])[CH:19]=3)=[CH:13][CH:14]=2)=[CH:4][C:3]=1[C:25]([F:28])([F:26])[F:27]

Participants

3

Reactant 2

HCID 21698362HCID 21698362, compoundHCID 67958335HCID 67958335, compound

Product 1

HCID 57383265HCID 57383265, compound

Procedure

The title compound was prepared by a procedure similar to that described for E21 starting from 4-{[2-(4-{[4-chloro-3-(trifluoromethyl)phenyl]oxy}phenyl)ethyl]oxy}-2 (1H)-pyridinone and 4-(Chloromethyl)-1-methyl-1H-pyrazole. LC-MS (ESI): m/z 504 [M+H]+; 3.68 min (ret time).

Workup

  1. custom3.68 min (ret time)

Sources & evidence

ORD record
ord-5ab6e2483e334ad5b7cb60243a12f5dd
Source dataset
uspto-grants-2014_10
Patent number
US08859573B2

Reaction notes

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