HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyanogen Bromide → 8-methoxy-2,3-dihydroimidazo[1,2-c]quinazolin-5-amine;hydrobromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyanogen Bromide | HCID 10476 | — |
| Reactant | 2-(4,5-dihydro-1H-imidazol-2-yl)-5-methoxyaniline | HCID 58377389 | — |
| Product | 8-methoxy-2,3-dihydroimidazo[1,2-c]quinazolin-5-amine;hydrobromide | HCID 178419595 | — |
Reaction Steps
The procedure used for the preparation of Intermediate C, Step 4 was used to prepare the title compound from 2-(4,5-dihydro-1H-imidazol-2-yl)-5-methoxyaniline (Step 2) and cyanogen bromide as a yellow solid (7.1 g, 56%). HPLC MS RT=1.07 min, [M-HBr+H]+=217.2
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08859572B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-19a696ce108f464e8652bba74a434822 |
| Source note | uspto-grants-2014_10 |