Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 536346Generated: October 29, 2026

1-Bromo-2,5-dimethyl-4-nitrobenzene → tert-Butyl 3-(2,5-dimethyl-4-nitrophenyl)azetidine-1-carboxylate

https://huagongshe.com/reaction/536346

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Bromo-2,5-dimethyl-4-nitrobenzeneHCID 825808—
ReactantTert-butyl 3-iodoazetidine-1-carboxylateHCID 11000522—
Producttert-Butyl 3-(2,5-dimethyl-4-nitrophenyl)azetidine-1-carboxylateHCID 86653270—

Reaction Steps

Prepared from tert-butyl 3-iodoazetidine-1-carboxylate and 1-bromo-2,5-dimethyl-4-nitrobenzene by following the general protocol as described in Billotte, S. Synlett 1998, 379.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08859574B2
Source datasetuspto-grants-2014_10
ORD IDord-2b43e6fab4dd49cd8491a7f0fed4c7ef
Source noteuspto-grants-2014_10