Ammonia → 7-(Trifluoromethyl)chroman-4-one

HRID 536461Notes

Reaction equation

[F:1][C:2]([F:11])([F:10])[C:3]1[CH:4]=[C:5]([OH:9])[CH:6]=[CH:7][CH:8]=1.N>>[F:1][C:2]([F:10])([F:11])[C:3]1[CH:4]=[C:5]2[C:6]([C:5](=[O:9])[CH2:4][CH2:3][O:9]2)=[CH:7][CH:8]=1

Participants

Reactant 2

HCID 222Ammonia

HCID 73763-(Trifluoromethyl)phenol

Product 1

HCID 139538217-(Trifluoromethyl)chroman-4-one

Procedure

The title compound was prepared from 3-trifluoromethyl-phenol according to EP1908753. MS (DCI/NH3) m/z 234 (M+NH4)+.

Sources & evidence

ORD record: ord-45894c3b7656415498bb3990a07f9d36
Source dataset: uspto-grants-2014_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08859584B2

Reaction notes

Loading…