1-Propanol → HCID 71285790, compound

Participants

Reaction Steps

Under argon, 80 mg (0.20 mmol) of the compound from example 109, 13 mg (16 μl, 0.22 mmol) of n-propanol and 57 mg (0.22 mmol) of triphenyl phosphine were suspended in 0.8 ml THF, mixed for 10 min in the ultrasonic bath and finally 44 mg (43 μl, 0.22 mmol) of diisopropyl azodicarboxylate was added and it was stirred for 1 h at RT. The reaction mixture was purified by preparative HPLC (Reprosil C18, gradient of acetonitrile/0.01% aq. formic acid). Yield: 48 mg (55% of theor.)

Provenance & Evidence