Allylhydrazine → 1-allyl-3-tert-butyl-1H-pyrazol-5-amine

HRID 536714Notes

Reaction equation

[CH2:1]([NH:4][NH2:5])[CH:2]=[CH2:3].[CH3:6][C:7]([CH3:14])([CH3:13])[C:8](=O)[CH2:9][C:10]#[N:11]>>[CH2:1]([N:4]1[C:10]([NH2:11])=[CH:9][C:8]([C:7]([CH3:14])([CH3:13])[CH3:6])=[N:5]1)[CH:2]=[CH2:3]

Participants

Reactant 2

HCID 81921Allylhydrazine

HCID 108871Pentanenitrile, 4,4-dimethyl-3-oxo-

Product 1

HCID 666431541-allyl-3-tert-butyl-1H-pyrazol-5-amine

Procedure

Allylhydrazine (70% in water, Wako) and 4,4-dimethyl-3-oxopentanenitrile (Aldrich) were processed as described for Example 30A to obtain the title compound. MS (ESI+) m/z 180 (M+H)+.

Sources & evidence

ORD record: ord-fc489acdbce2413ba991213ce4510deb
Source dataset: uspto-grants-2014_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08859596B2

Reaction notes

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