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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 53676Generated: October 28, 2026

4-Chloro-2-dimethylamino-pyrimidine-5-carboxylic acid benzylamide → HCID 178418259, compound

https://huagongshe.com/reaction/53676

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chloro-2-dimethylamino-pyrimidine-5-carboxylic acid benzylamideHCID 53723042—
ReactantSodium hydrogen sulphideHCID 86586439—
ProductHCID 178418259HCID 17841825943.9%

Reaction Steps

Using the procedure of Preparation 34, 14.3 g (0.045 mol) of 4-chloro-2-dimethylamino-pyrimidine-5-carboxylic acid benzylamide and 12 g (0.21 mol) of sodium hydrogen sulfide were reacted to give 5.7 g of the title compound, mp 175°-178° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05620997
Source datasetuspto-grants-1997_04
ORD IDord-83c3195b847143f7ba2b9dd6d5c671fd
Source noteuspto-grants-1997_04