HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Tetramethyl-1,3,2-dioxaborolan-2-yl)aniline → 1-(4-(4-(4-Aminophenyl)-6-morpholino-1,3,5-triazin-2-yl)phenyl)-3-methylurea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Tetramethyl-1,3,2-dioxaborolan-2-yl)aniline | HCID 2734620 | — |
| Reactant | 1-(4-(4-Chloro-6-morpholino-1,3,5-triazin-2-yl)phenyl)-3-methylurea | HCID 86636523 | — |
| Product | 1-(4-(4-(4-Aminophenyl)-6-morpholino-1,3,5-triazin-2-yl)phenyl)-3-methylurea | HCID 67438523 | 45% |
Reaction Steps
The title compound was prepared by following the procedure of Example 462 step 4 using 1-(4-(4-chloro-6-morpholino-1,3,5-triazin-2-yl)phenyl)-3-methylurea and 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline. Yield 2 g, 45% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08859542B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-a28291e524e94d85aef3ce486eaa8b0e |
| Source note | uspto-grants-2014_10 |