HuagongsheHuagongshe Chemistry Print Report · For research reference only
phenyl N-(3-carbamoylphenyl)carbamate → 3-[({4-[4-(3,5-Dimethylmorpholin-4-yl)-6-{4-[(methylcarbamoyl)amino]phenyl}-1,3,5-triazin-2-yl]phenyl}carbamoyl)amino]benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | phenyl N-(3-carbamoylphenyl)carbamate | HCID 60630270 | — |
| Reactant | 1-(4-(4-(4-Aminophenyl)-6-(3,5-dimethyl morpholino)-1,3,5-triazin-2-yl)phenyl)-3-methylurea | HCID 67438018 | — |
| Product | 3-[({4-[4-(3,5-Dimethylmorpholin-4-yl)-6-{4-[(methylcarbamoyl)amino]phenyl}-1,3,5-triazin-2-yl]phenyl}carbamoyl)amino]benzamide | HCID 66585609 | 4.1% |
Reaction Steps
The title compound was prepared by following the procedure of example 462 step 7 using 1-(4-(4-(4-aminophenyl)-6-(3,5-dimethylmorpholino)-1,3,5-triazin-2-yl)phenyl)-3-methylurea and phenyl 3-carbamoylphenylcarbamate. Yield 56 mg, 4.1% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08859542B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-d3c027db7cbf487591b7fda6f357f713 |
| Source note | uspto-grants-2014_10 |