HuagongsheHuagongshe Chemistry Print Report · For research reference only
Carbamic acid, 4-pyridinyl-, phenyl ester → 1-{4-[4-(3,5-Dimethylmorpholin-4-yl)-6-{4-[(methylcarbamoyl)amino]phenyl}-1,3,5-triazin-2-yl]phenyl}-3-pyridin-4-ylurea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Carbamic acid, 4-pyridinyl-, phenyl ester | HCID 11401617 | — |
| Reactant | 1-(4-(4-(4-Aminophenyl)-6-(3,5-dimethyl morpholino)-1,3,5-triazin-2-yl)phenyl)-3-methylurea | HCID 67438018 | — |
| Product | 1-{4-[4-(3,5-Dimethylmorpholin-4-yl)-6-{4-[(methylcarbamoyl)amino]phenyl}-1,3,5-triazin-2-yl]phenyl}-3-pyridin-4-ylurea | HCID 66585611 | 0.8% |
Reaction Steps
The title compound was prepared by following the procedure of example 462 step 7 using 1-(4-(4-(4-aminophenyl)-6-(3,5-dimethylmorpholino)-1,3,5-triazin-2-yl)phenyl)-3-methylurea and phenyl pyridin-4-ylcarbamate. Yield 15 mg, 0.8% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08859542B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-8195f325f0dd4512b75c1f1911d084a4 |
| Source note | uspto-grants-2014_10 |