Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 536963Generated: October 30, 2026

Ammonia → HCID 58994939, compound

https://huagongshe.com/reaction/536963

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniaHCID 222—
Reactant1,4-DioxaneHCID 31275—
Reactant4-Nitrophenyl chloroformateHCID 82129—
Reactant4-(4-Nitrophenyl)piperidine-4-carbonitrileHCID 57416099—
ProductHCID 58994939HCID 58994939—

Reaction Steps

The title compound is prepared from 4-(4-nitro-phenyl)-piperidine-4-carbonitrile (as prepared in Example 77, step (a)) using 4-nitro-phenyl chloroformate and ammonia in 1,4-dioxane according to the procedure in QSAR & Combinatorial Science, 23(10), 854-858 (2004).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08859602B2
Source datasetuspto-grants-2014_10
ORD IDord-1bdc09a3cbca4a24af19cb4b5cc5ebe7
Source noteuspto-grants-2014_10