Hydrochloric Acid → (1S,2R,4R)-1,2-bis((7,7-dimethyl-2-morpholinobicyclo[2.2.1]heptan-1-yl)methyl)disulfane hydrochloride

Participants

Reaction Steps

To a solution (1S,2R,4R)-1,2-bis((7,7-dimethyl-2-morpholinobicyclo[2.2.1]heptan-1-yl)methyl)disulfane (IIIa) (111 mg, 0.22 mmol) in IPA (1 mL) and n-heptane (2 mL) was added a solution of HCl in IPA (1 mL, 4.9 mmol). The resulting mixture was concentrated in vacuo to give the title product (1S,2R,4R)-1,2-bis((7,7-dimethyl-2-morpholinobicyclo[2.2.1]heptan-1-yl)methyl)disulfane hydrochloride (IIIb) as a white powder.

Provenance & Evidence