Trifluoroacetic acid → HCID 178474095, compound

Participants

Reaction Steps

TFA (0.6 mL) was added to a solution of N-{4-[5-(2-chlorophenyl)-4-(4-{[2-(trimethylsilyl)ethoxy]methyl}-4H-1,2,4-triazol-3-yl)-1,3-oxazol-2-yl]phenyl}acetamide (0.10 g, 0.20 mmol) in DCM (3 mL). The reaction mixture was allowed to stir at rt overnight and then concentrated. The residue was purified by column chromatography to give N-{4-[5-(2-chlorophenyl)-4-(1H-1,2,4-triazol-3-yl)-1,3-oxazol-2-yl]phenyl}acetamide (Compound I-8) (0.026 g, 32%). LCMS (FA): m/z=380 (M+H).

Provenance & Evidence