Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 4-(3-benzyloxyphenyl)-1-(3-cyclohexylpropyl)-4-fluoro-3-methylpiperidine Hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | (3-Bromopropyl)cyclohexane | HCID 96426 | — |
| 반응물 | 4-(3-Benzyloxyphenyl)-4-fluoro-3-methylpiperidine hydrochloride | HCID 67463151 | — |
| 생성물 | 4-(3-benzyloxyphenyl)-1-(3-cyclohexylpropyl)-4-fluoro-3-methylpiperidine Hydrochloride | HCID 67461568 | — |
반응 단계
This material was prepared by the alkylation of 4-(3-benzyloxyphenyl)-4-fluoro-3-methylpiperidine hydrochloride with 1-bromo-3-cyclohexylpropane and subsequent salt formation with methanolic hydrogen chloride as described in Step 3 of Example 1 in 48% overall yield.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08859777B2 |
| 출처 데이터셋 | uspto-grants-2014_10 |
| ORD ID | ord-5422a3d1598a4440a34e5006442913eb |
| 출처 메모 | uspto-grants-2014_10 |