Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
n-(4-Bromophenyl)prop-2-enamide → 3-[4-(3-Benzyloxyphenyl)-4-fluoro-3-methylpiperidin-1-yl]-N-(4-bromophenyl)propionamide Hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | n-(4-Bromophenyl)prop-2-enamide | HCID 263609 | — |
| 반응물 | 4-(3-Benzyloxyphenyl)-4-fluoro-3-methylpiperidine hydrochloride | HCID 67463151 | — |
| 생성물 | 3-[4-(3-Benzyloxyphenyl)-4-fluoro-3-methylpiperidin-1-yl]-N-(4-bromophenyl)propionamide Hydrochloride | HCID 67466167 | 65% |
반응 단계
This material was synthesized by the reaction of N-(4-bromophenyl)acrylamide with 4-(3-benzyloxyphenyl)-4-fluoro-3-methylpiperidine hydrochloride as described in Step 1 of Example 20. The desired compound was obtained as a light yellow solid in 65% yield.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08859777B2 |
| 출처 데이터셋 | uspto-grants-2014_10 |
| ORD ID | ord-d2e7d9b1ce0242a1a89b3899e65e236c |
| 출처 메모 | uspto-grants-2014_10 |