HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl 4-oxopiperidine-1-carboxylate → tert-Butyl 4-hydroxy-4-(3-methoxyphenyl)piperidine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl 4-oxopiperidine-1-carboxylate | HCID 735900 | — |
| Reactant | HCID 178490745 | HCID 178490745 | — |
| Product | tert-Butyl 4-hydroxy-4-(3-methoxyphenyl)piperidine-1-carboxylate | HCID 49760242 | 55% |
Reaction Steps
This compound was prepared from tert-Butyl 4-oxopiperidine-1-carboxylate and 3-methoxyphenylmagnesium bromide as described in Step 1 of Example 6 in 55% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08859777B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-c21be25e33c04ffbad1b1426124cdd12 |
| Source note | uspto-grants-2014_10 |