5,5-Dimethylpyrrolidine-2,4-dione → 8-Methoxy-3-phenyl-1-azaspiro[4.5]decane-2,4-dione

Participants

Reaction Steps

The procedure is as in Example 1, except that 1.532 g of methyl 8-methoxy-2,4-dioxo-1-azaspiro[4.5]decane-3-carboxylate as in Example (X-2-a-1) are used instead of 5,5-dimethyl-pyrrolidine-2,4-dione. This gives the title compound in a yield of approximately 90% of theory.

Provenance & Evidence