Acetic Acid → HCID 67164001, compound

Participants

Reaction Steps

33.6 g (0.146 mol) of 3,3,6,6-tetramethyl-4,5-octanedione, 22.51 g (0.292 moles) of ammonium acetate and 50.1 mL (0.0.876 moles) of acetic acid were refluxed to 140° C. overnight. The resulting product mixture was neutralized with sodium bicarbonate solution, then extracted with hexanes. The aqueous layer was washed 3× with 100 mL of hexanes. The hexane layer was washed 3× with 100 mL of water then stood over 20 g of anhydrous magnesium sulfate for 2 hrs then removed by filtration. Hexanes was then removed by vacuum, yield 27.6 g (92%). Characterized by Mass Spectrometry: Parent ion at 207 m.u

Provenance & Evidence