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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 537342Generated: October 29, 2026

(1r,2s,5s)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylic acid methyl ester → HCID 20782721, compound

https://huagongshe.com/reaction/537342

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1r,2s,5s)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylic acid methyl esterHCID 11229499—
ReactantHCID 25013535HCID 25013535—
ProductHCID 20782721HCID 20782721—

Reaction Steps

The (1R,2S,5S)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carbonitrile prepared according to Example 16 or 17 is converted to the corresponding substantially enantiomerically pure (1R,2S,5S)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylic acid methyl ester by the procedure described in PCT International Application Publication WO 2007/075790.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08859784B2
Source datasetuspto-grants-2014_10
ORD IDord-768546c6d2434d21a6bc02483ce6f7d9
Source noteuspto-grants-2014_10