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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 537400Generated: October 25, 2026

2-Chlorocinnamaldehyde → HCID 131731951, compound

https://huagongshe.com/reaction/537400

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-ChlorocinnamaldehydeHCID 3014042—
ReactantHCID 11480472HCID 11480472—
ReactantTert-butyl{3-(2-chlorophenyl)-1-[(4-methylpiperidin-1-yl)carbonyl]propyl}carbamateHCID 131731949—
ProductHCID 131731951HCID 131731951—

Reaction Steps

tert-Butyl{1-[(4-methylpiperidin-1-yl)carbonyl]-3-pyridin-4-ylpropyl}carbamate is prepared from pyridin-4-yl propionaldehyde (Kitbunnadaj, R. et al. J. Med. Chem, 2004, 47, 2414-2417) in the same manner that tert-butyl{3-(2-chlorophenyl)-1-[(4-methylpiperidin-1-yl)carbonyl]propyl}carbamate is prepared from 3-(2-chlorophenyl)propenal in Example 5.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08859814B2
Source datasetuspto-grants-2014_10
ORD IDord-61a3f82598af46388a71da91639c2d65
Source noteuspto-grants-2014_10