1-Bromo-2-iodobenzene → HCID 91378583, compound

HRID 537404Notes

Reaction equation

HRID 537404 reaction equation
I[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[Br:8].[C:9]([O:13][C:14](=[O:35])[NH:15][CH:16]([C:26]([N:28]1[CH2:33][CH2:32][CH:31]([CH3:34])[CH2:30][CH2:29]1)=[O:27])[CH2:17][CH2:18]C1C=CC=CC=1Cl)([CH3:12])([CH3:11])[CH3:10]>>[C:9]([O:13][C:14](=[O:35])[NH:15][CH:16]([C:26]([N:28]1[CH2:33][CH2:32][CH:31]([CH3:34])[CH2:30][CH2:29]1)=[O:27])[CH2:17][CH2:18][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[Br:8])([CH3:10])([CH3:11])[CH3:12]

Participants

3

Reactant 2

HCID 114151-Bromo-2-iodobenzeneHCID 131731949Tert-butyl{3-(2-chlorophenyl)-1-[(4-methylpiperidin-1-yl)carbonyl]propyl}carbamate

Product 1

HCID 91378583HCID 91378583, compound

Procedure

tert-Butyl{3-(2-bromophenyl)-1-[(4-methylpiperidin-1-yl)carbonyl]propyl}carbamate is prepared from 2-iodobromobenzene in the same manner that tert-butyl{3-(2-chlorophenyl)-1-[(4-methylpiperidin-1-yl)carbonyl]propyl}carbamate is synthesized.

Workup

  1. customis synthesized

Sources & evidence

ORD record
ord-5e9c896b8c4a4fbab20352d26b0df956
Source dataset
uspto-grants-2014_10
Patent number
US08859814B2

Reaction notes

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