HCID 66997971, compound → HCID 58504878, compound

HRID 537412Notes

Reaction equation

HRID 537412 reaction equation
C(OC([NH:8][CH:9]([C:21]([N:23]1[CH2:28][CH2:27][CH:26]([CH3:29])[CH2:25][CH2:24]1)=[O:22])[CH2:10][CH2:11][C:12]1[CH:13]=[C:14]([CH:18]=[CH:19][CH:20]=1)[C:15]([OH:17])=[O:16])=O)(C)(C)C.C(OC([N:37]1[C:45]2[CH:44]=[CH:43][CH:42]=[C:41]([S:46]([OH:48])=[O:47])[C:40]=2[CH:39]=[CH:38]1)=O)(C)(C)C.[Li]>>[NH:37]1[C:45]2[C:40](=[C:41]([S:46]([NH:8][CH:9]([C:21]([N:23]3[CH2:24][CH2:25][CH:26]([CH3:29])[CH2:27][CH2:28]3)=[O:22])[CH2:10][CH2:11][C:12]3[CH:13]=[C:14]([CH:18]=[CH:19][CH:20]=3)[C:15]([OH:17])=[O:16])(=[O:48])=[O:47])[CH:42]=[CH:43][CH:44]=2)[CH:39]=[CH:38]1

Participants

3

Reactant 2

HCID 66997971HCID 66997971, compoundHCID 131731953HCID 131731953, compound

Product 1

HCID 58504878HCID 58504878, compound

Procedure

Example 84 is prepared from 3-[3-tert-butoxycarbonylamino-4-(4-methyl-piperidin-1-yl)-4-oxo-butyl]-benzoic acid and lithum 1-(tert-butoxycarbonyl)-1H-indole-4-sulfinic acid in the same manner as Example 71. ESI MS Calc. 483.2; Found. 484.8 (M+H)+.

Sources & evidence

ORD record
ord-ccb1ea8b730a44f3a427ec52d0d0bb34
Source dataset
uspto-grants-2014_10
Patent number
US08859814B2

Reaction notes

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