Phenol → HCID 58504880, compound

HRID 537415Notes

Reaction equation

HRID 537415 reaction equation
[Cl:1][C:2]1[CH:8]=[C:7]([S:9]([N:12]2[CH2:14][CH:13]2[C:15]([N:17]2[CH2:22][CH2:21][CH:20]([CH3:23])[CH2:19][CH2:18]2)=[O:16])(=[O:11])=[O:10])[CH:6]=[C:5]([Cl:24])[C:3]=1[NH2:4].[C:25]1([OH:31])[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1>>[NH2:4][C:3]1[C:2]([Cl:1])=[CH:8][C:7]([S:9]([NH:12][CH:13]([CH2:14][O:31][C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[C:15]([N:17]2[CH2:22][CH2:21][CH:20]([CH3:23])[CH2:19][CH2:18]2)=[O:16])(=[O:11])=[O:10])=[CH:6][C:5]=1[Cl:24]

Participants

3

Reactant 2

HCID 996PhenolHCID 86659049HCID 86659049, compound

Product 1

HCID 58504880HCID 58504880, compound

Procedure

Examples 100-105 are prepared from 2,6-dichloro-4-({2-[(4-methylpiperidin-1-yl)carbonyl]aziridin-1-yl}sulfonyl)aniline and the appropriate phenol in the same manner that Example 99 is synthesized.

Sources & evidence

ORD record
ord-f4de408187cd42d38e725a0a27f3af71
Source dataset
uspto-grants-2014_10
Patent number
US08859814B2

Reaction notes

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