HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → 3,5-Di(docosyloxy)benzylchloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | (3,5-Bis(docosyloxy)phenyl)methanol | HCID 49844210 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 3,5-Di(docosyloxy)benzylchloride | HCID 67248881 | 99% |
Reaction Steps
3,5-Di(docosyloxy)benzyl alcohol (500 mg, 0.66 mmol) was dissolved in chloroform (5 ml), thionyl chloride (71 μl, 0.99 mmol) and DMF (10 μl, 0.13 mmol) were added dropwise, and the mixture was stirred at room temperature for 1 hr. The solvent was evaporated, and the residue was precipitated with acetonitrile to give 3,5-di(docosyloxy)benzylchloride (505 mg, 0.65 mmol, 99%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08859732B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-a55ffefb20634d1eaf92056681814744 |
| Source note | uspto-grants-2014_10 |