HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 67513216, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Trimethylsilylacetylene | HCID 66111 | — |
| Reactant | HCID 68026255 | HCID 68026255 | — |
| Catalyst | Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI) | HCID 24350 | — |
| Catalyst | HCID 178418476 | HCID 178418476 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 67513216 | HCID 67513216 | — |
Reaction Steps
2.4 Reaction of tert-butyl 7-iodo-2-(1-methyl-1H-pyrazol-4-yl)pyrrolo-[2,3-b]pyrazine-5-carboxylate with bis(triphenylphosphine)palladium dichloride, copper(I) iodide, trimethylsilylacetylene and triethylamine in THF analogously to Example 1.3 gives tert-butyl 2(1-methylpyrazol-4-yl)-7-(2-trimethylsilylethynyl)pyrrolo[2,3-b]pyrazine-5-carboxylate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08865715B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-49d48717f4f14b56b28a334c41cc3db8 |
| Source note | uspto-grants-2014_10 |