HCID 66584459, compound → HCID 66584507, compound

HRID 538015Notes

Reaction equation

HRID 538015 reaction equation
S(O[CH2:12][CH2:13][CH2:14][CH:15]1[CH2:20][CH2:19][N:18]([C:21]2[CH:26]=[CH:25][C:24]([N+:27]([O-:29])=[O:28])=[CH:23][CH:22]=2)[CH2:17][CH2:16]1)(C1C=CC(C)=CC=1)(=O)=O.[N:30]1(C(C)CC2CCN(C3C=CC(N)=CC=3)CC2)[CH:34]=[CH:33][N:32]=[N:31]1>>[N:30]1([CH2:12][CH2:13][CH2:14][CH:15]2[CH2:16][CH2:17][N:18]([C:21]3[CH:22]=[CH:23][C:24]([N+:27]([O-:29])=[O:28])=[CH:25][CH:26]=3)[CH2:19][CH2:20]2)[CH:34]=[CH:33][N:32]=[N:31]1

Participants

3

Reactant 2

HCID 66584459HCID 66584459, compoundHCID 86660670HCID 86660670, compound

Product 1

HCID 66584507HCID 66584507, compound

Procedure

Following the procedure of Example 7(1), the 4-tosyloxypropyl-N-(4-nitrophenyl)piperidine obtained in Example 11(2) was used instead of 4-tosyloxyethyl-N-(4-nitrophenyl)piperidine, thereby obtaining 4-[2-(1,2,3-triazol-1-yl)-propyl]-N-(4-aminophenyl)piperidine (69%) as a yellow solid.

Sources & evidence

ORD record
ord-88e72152517545efadc95b7abb77a846
Source dataset
uspto-grants-2014_10
Patent number
US08865714B2

Reaction notes

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