HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-4-methylbenzothiazole → 2,6-Difluoro-3-[(4-methyl-1,3-benzothiazol-2-yl)methoxy]benzenecarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-4-methylbenzothiazole | HCID 15132 | — |
| Reactant | 3-(Cyanomethoxy)-2,6-difluorobenzenecarboxamide | HCID 59402804 | — |
| Product | 2,6-Difluoro-3-[(4-methyl-1,3-benzothiazol-2-yl)methoxy]benzenecarboxamide | HCID 46237267 | 36% |
Reaction Steps
Synthesised from 4-methyl-1,3-benzothiazol-2-amine and 3-(cyanomethoxy)-2,6-difluorobenzene carboxamide, according to Method K, scheme 26. Yield 36% (second step), mp 201-202° C., HPLC-MS (method 1): m/z 335 [M+H]+, Rt=3.79 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08865736B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-08c46133eca9495bb784814ae5fd452f |
| Source note | uspto-grants-2014_10 |