2,6-Diisopropyl-4-(2-nitrostyryl)phenol → 4-(2-Aminophenethyl)-2,6-diisopropylphenol

Participants

Reaction Steps

To a suspension of 2,6-diisopropyl-4-(2nitrostyryl)phenol (1.3 g, 4.0 mmol) in ethanol (20 ml) was added a catalytic amount of 10% palladium carbon and the suspension was subjected to catalytic reduction at 1-2.5 atms at room temperature for 7 hrs. After filtering the catalyst, distilling off the solvent gave 4-(2-aminophenethyl)-2,6-diisopropylphenol (1.0 g, 84%) as a viscous oil.

Provenance & Evidence