Succinimide → HCID 25116543, compound

HRID 538704Notes

Reaction equation

Cl[CH2:2][C:3]([N:5]1[CH2:10][CH2:9][CH:8]([N:11]2[C:15](=[O:16])[C:14]([CH2:18][CH3:19])([CH3:17])[C:13]([C:20]3[CH:25]=[CH:24][C:23]([O:26][CH3:27])=[C:22]([O:28][CH3:29])[CH:21]=3)=[N:12]2)[CH2:7][CH2:6]1)=[O:4].[C:30]1(=[O:36])[NH:34][C:33](=[O:35])[CH2:32][CH2:31]1>>[CH3:29][O:28][C:22]1[CH:21]=[C:20]([C:13]2[C:14]([CH2:18][CH3:19])([CH3:17])[C:15](=[O:16])[N:11]([CH:8]3[CH2:7][CH2:6][N:5]([C:3](=[O:4])[CH2:2][N:34]4[C:30](=[O:36])[CH2:31][CH2:32][C:33]4=[O:35])[CH2:10][CH2:9]3)[N:12]=2)[CH:25]=[CH:24][C:23]=1[O:26][CH3:27]

Participants

Reactant 2

HCID 11439Succinimide

HCID 66616576HCID 66616576, compound2×

Product 1

HCID 25116543HCID 25116543, compound

Procedure

Prepared analogously as described for example 1 using 2-[1-(chloroacetyl)piperidin-4-yl]-5-(3,4-dimethoxyphenyl)-4-ethyl-4-methyl-2,4-dihydro-3H-pyrazol-3-one (compound A9) and succinimide as starting compounds.

Workup

customPrepared analogously

Sources & evidence

ORD record: ord-b85f69abec274a94a3536f6990d42bcf
Source dataset: uspto-grants-2014_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08865745B2

Reaction notes

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