Sodium Hydroxide → HCID 86669078, compound

HRID 538756Notes

Reaction equation

HRID 538756 reaction equation
[C:1]([NH:14][C@H:15]([C:24]([OH:26])=[O:25])[CH2:16][CH2:17][CH2:18][CH2:19][NH:20][N:21]=[C:22]=[S:23])(=[O:13])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].[OH-].[Na+:28]>O>[C:1]([NH:14][C@H:15]([C:24]([O-:26])=[O:25])[CH2:16][CH2:17][CH2:18][CH2:19][NH:20][N:21]=[C:22]=[S:23])(=[O:13])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].[Na+:28]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 86669079HCID 86669079, compound

Product 1

HCID 86669078HCID 86669078, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

0.147 g of Nα-lauroyl-Nε-isothiocyanato-L-Lysine was combined and stirred with 2 g of RO water and 0.39 mL of 1.00 M NaOH in a 50 mL single neck round bottom flask and filtered into a 250 mL single neck round bottom flask to yield a clear pale amber solution. The flask was then immersed while rotating into a dry ice/acetone bath to yield a solid coating on the walls of the flask, whereupon the flask was evacuated (0.10 mm Hg) and removed from the ice bath. Evacuation for one hour yielded a dry white solid powder of the water soluble surfactant Sodium Nα-lauroyl-Nε-isothiocyanato-L-Lysinate. [mp 47-55° C. to small droplets of clear colorless viscous liquid; IR (mineral oil mull, cm−1), 3300m amide N—H str; 2188s, 2107s N═C str; 1627s, amide C═O str; 1593s carboxylate C═O str]

Workup

  1. filtrationfiltered into a 250 mL single neck round bottom flask
  2. customto yield a clear pale amber solution
  3. customwhile rotating into a dry ice/acetone bath
  4. customto yield a solid coating on the walls of the flask
  5. customwhereupon the flask was evacuated (0.10 mm Hg)
  6. customremoved from the ice bath
  7. customEvacuation for one hour yielded a dry white solid powder of the water soluble surfactant Sodium Nα-lauroyl-Nε-isothiocyanato-L-Lysinate

Sources & evidence

ORD record
ord-441b12f7de084aec895ca2909b374bea
Source dataset
uspto-grants-2014_10
Patent number
US08865765B2

Reaction notes

Loading…