Iodine → HCID 66851797, compound

Participants

Reaction Steps

A mixture of 3,3-dimethylbutanal (3.0 mL, 24 mmol), 3-methylbutan-1-amine (2.5 mL, 22 mmol), 4 Å molecular sieves (3 g, 8-12 mesh beads), potassium thiocyanate (2.8 g, 29 mmol) and iodine (11 g, 44 mmol) in acetonitrile (40 mL) were processed as described in Example 18A to provide the title compound (4.9 g, 23 mol, 99% yield). MS (DCI/NH3) m/z 227 (M+H)+.

Provenance & Evidence