Butyl bromide → HCID 66851701, compound

Participants

Reaction Steps

A mixture of Example 96A (290 mg, 1.86 mmol) and 1-bromobutane (220 μL, 2.0 mmol) in DMF (400 μL) was heated at 95° C. for 16 hr, cooled to room temperature and quenched with 5 mL of aqueous 1M NaHCO3 solution. The aqueous layer was extracted with dichloromethane (3×5 mL). The combined organic extracts were dried (Na2SO4), filtered and concentrated to afford 0.4 g of the crude product of the title compound. LC/MS (ESI+) m/z 213 (M+H)+.

Provenance & Evidence