m-Chloroperbenzoic acid → HCID 86694360, compound

Participants

Reaction Steps

To a suspension of tert-butyl cyclopent-2-en-1-yl((2-nitrophenyl)sulfonyl)carbamate (2.75 g, 7.46 mmol) and NaHCO3 (1.254 g, 14.93 mmol) in CH2Cl2 (60 mL) was added in one portion meta-chloroperoxybenzoic acid (2.58 g, 14.93 mmol). The resulting reaction mixture was stirred overnight at RT. The reaction mixture was diluted with CH2Cl2 and washed with 20% aqueous Na2SO3 solution, saturated NaHCO3 solution and water. The organic phase was dried over MgSO4 and concenrated. The title compound was obtained after crystallization from EtOAc as white crystals (2.01 g, 68%): TLC (heptane-EtOAc 1:1) Rf=0.48; tR=1.20 min (UPLC 1), tR=1.12 min (LC-MS 3); ESI-MS: 329 [M-isobutylene]+ (LC-MS 3).

Provenance & Evidence