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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 538968Generated: October 26, 2026

Ammonia → 1,1-Cyclohexanedicarboxamide

https://huagongshe.com/reaction/538968

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniaHCID 222—
ReactantThionyl ChlorideHCID 24386—
ReactantCyclohexane-1,1-dicarboxylic acidHCID 136906—
Reactant1,1-CyclohexanedicarboxamideHCID 299204—
Product1,1-CyclohexanedicarboxamideHCID 299204—
Product1,1-CyclohexanedicarbonitrileHCID 544561—

Reaction Steps

Furthermore, as a method for producing bis(aminomethyl)cyclohexane, for example, Non-Patent Document 1 (Malachowski et al.) discloses the following: an acid chloride derivative is prepared using cyclohexanedicarboxylic acid with thionyl chloride; cyclohexane diamide is prepared using the acid chloride derivative with ammonia; and thereafter, the cyclohexane diamide is further allowed to react with thionyl chloride to obtain dicyanocyclohexane, and then the obtained dicyanocyclohexane is hydrogenated.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08865938B2
Source datasetuspto-grants-2014_10
ORD IDord-17d89f5f75154560a35f326706e8dd50
Source noteuspto-grants-2014_10