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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 539089Generated: October 31, 2026

HCID 67034361, compound → HCID 178519148, compound

https://huagongshe.com/reaction/539089

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 67034361HCID 67034361—
ReactantHCID 67034473HCID 67034473—
ProductHCID 178519148HCID 17851914881%

Reaction Steps

(R)-4-(3,4-difluorophenyl)-3-(3-(3-fluoro-4-(1H-1,2,4-triazol-3-yl)phenyl)pyrazolo[1,5-a]pyrimidin-5-yl)oxazolidin-2-one (16 mg, 81%) was prepared by the procedure described in Example 1, Step 9, using a mixture of (R)-4-(3,4-difluorophenyl)-3-(3-(3-fluoro-4-(1-((2-(trimethylsilyl)ethoxy)methyl)-1H-1,2,4-triazol-3-yl)phenyl)pyrazolo[1,5-a]pyrimidin-5-yl)oxazolidin-2-one and (R)-4-(3,4-difluorophenyl)-3-(3-(3-fluoro-4-(1-((2-(trimethylsilyl) ethoxy)methyl)-1H-1,2,4-triazol-5-yl)phenyl)pyrazolo [1,5-a]pyrimidin-5-yl)oxazolidin-2-one. LCMS (APCI+) m/z 478.2 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08865726B2
Source datasetuspto-grants-2014_10
ORD IDord-abb7475f163e4a72a5e29bb7dc6f210f
Source noteuspto-grants-2014_10