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HRID539095

反应详情

EQUATION

反应方程式

HRID 539095 的结构方程式

REACTANTS

反应物

2
结构：CC(C)(C)OC(=O)N1CCN(c2ccccc2C2COC(=O)N2c2ccn3ncc(-c4ccc(-c5ncnn5COCC[Si](C)(C)C)c(F)c4)c3n2)CC1
HCID68088754

未命名化合物

结构：CC(C)(C)OC(=O)N1CCN(c2ccccc2C2COC(=O)N2c2ccn3ncc(-c4ccc(-c5ncn(COCC[Si](C)(C)C)n5)c(F)c4)c3n2)CC1
HCID68088996

未命名化合物

PRODUCTS

生成物

1
结构：O=C1OCC(c2ccccc2N2CCNCC2)N1c1ccn2ncc(-c3ccc(-c4nc[nH]n4)c(F)c3)c2n1
HCID178519090

未命名化合物

收率 43%

PROCEDURE

实验过程

3-(3-(3-fluoro-4-(1H-1,2,4-triazol-3-yl)phenyl)pyrazolo[1,5-a]pyrimidin-5-yl)-4-(2-(piperazin-1-yl)phenyl)oxazolidin-2-one (36 mg, 43%) was prepared by the procedure described in Example 1, Step 9, using a mixture of tert-butyl 4-(2-(3-(3-(3-fluoro-4-(1-((2-(trimethylsilyl)ethoxy)methyl)-1H-1,2,4-triazol-3-yl)phenyl)pyrazolo[1,5-a]pyrimidin-5-yl)-2-oxooxazolidin-4-yl)phenyl)piperazine-1-carboxylate and tert-butyl 4-(2-(3-(3-(3-fluoro-4-(1-((2-(trimethylsilyl)ethoxy)methyl)-1H-1,2,4-triazol-5-yl)phenyl)pyrazolo[1,5-a]pyrimidin-5-yl)-2-oxooxazolidin-4-yl)phenyl)piperazine-1-carboxylate. LCMS (APCI+) m/z 526.1 [M+H]+.