Trifluoroacetic acid → HCID 25152743, compound

Participants

Reaction Steps

To a solution of 9 (8 mg, 0.011 mmol) in CH2Cl2 (1 mL) was added triethylsilane (7 μL, 0.44 mmol) was added dropwise TFA (0.2 mL, 20% v/v). After stirring for 1.5 h the reaction was concentrated in vacuo and purified by flash column chromatography (eluent 1:0-99:1-98:2-97:3-96.4 CH2Cl2/MeOH) to give the product 10 (0.47 mg, 0.001 mmol, 9%) as a white solid: Rf 0.44 MeOH/CH2Cl2 (1:9); MS (ES+) 584.2 (100%, [M+Na]+).

Provenance & Evidence