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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 539423Generated: October 31, 2026

Cyclohexanamine, 5-methyl-2-(1-methylethyl)- → HCID 86629952, compound

https://huagongshe.com/reaction/539423

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclohexanamine, 5-methyl-2-(1-methylethyl)-HCID 89497—
Reactant(3,4-Dimethoxyphenyl)acetyl chlorideHCID 3604458—
ProductHCID 86629952HCID 86629952—

Reaction Steps

The aforementioned product is obtained as a colorless solid containing in total 94.2% of the desired neomenthylamine derivatives from racemic neomenthylamine, as in the GP, by reaction with (3,4-dimethoxyphenyl)acetyl chloride. Furthermore, two further isomeric menthylamine derivatives are present at 2.7% and 2.5%, corresponding to a purity over all stereoisomers of 99.4%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08871288B2
Source datasetuspto-grants-2014_10
ORD IDord-a194433508cd411f83af680d51d55d99
Source noteuspto-grants-2014_10