2,2,3,3-Tetrafluoro-1-propanol → 1,1,1,2,3,3-Hexafluoro-3-(2,2,3,3-tetrafluoropropoxy)propane

Participants

Reaction Steps

Into a 3-liter autoclave were poured 84 g (1.35 mol) of KOH, 800 ml of H2O and 600 g (4.5 mol) of 2,2,3,3-tetrafluoropropanol: CHF2CF2CH2OH. Then, 681 g (4.5 mol) of hexafluoropropene: CF2═CFCF3 was introduced thereto. After completion of the reaction, the reaction solution was separated into two layers, and the lower layer was washed with water three times to separate the solution. After that, refining by distillation was carried out, and 1,015 g (3.6 mol) of a fluorine-containing chain ether (B1a): CHF2CF2CH2OCF2CHFCF3 was obtained (yield 80%).

Provenance & Evidence