関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | Pyridinium chloride | HCID 10176127 | — |
| 反応物 | 2-(3-methoxyphenyl)-1-phenyl-1H-imidazole | HCID 57128463 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 3-(1-phenyl-1H-imidazol-2-yl)phenol | HCID 70654534 | — |
反応手順
To a 500 mL round bottom flask was added 2-(3-methoxyphenyl)-1-phenyl-1H-imidazole (6.52 g, 26.0 mmol) and pyridine hydrochloride (24.08 g, 208 mmol). The reaction mixture was heated to 200° C. for 3 h under nitrogen. The reaction mixture was cooled to room temperature and the solid was added to water. The aqueous mixture was adjusted to pH 7 with sodium hydroxide solution. A gray solid was filtered off, washed with water, and dried (5.38 g, 83%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08871361B2 |
|---|
| 出典データセット | uspto-grants-2014_10 |
|---|
| ORD ID | ord-19ca3054e261458080412f09dfdb3ee9 |
|---|
| 出典メモ | uspto-grants-2014_10 |
|---|
