Lawesson's reagent → HCID 71139800, compound

Participants

Reaction Steps

A suspension of 141b (0.060 g, 0.28 mmol) and Lawesson's reagent (0.067 g, 0.17 mmol) in toluene (10 mL) was heated to reflux overnight. Reaction mixture was then cooled to room temperature. Toluene was evaporated in vacuo and resulting crude solid was directly loaded on prep-TLC. Elution with CH2Cl2:Acetone:MeOH (5:1:0.2) gave 143b 53 mg (82%) of yellow solid.

Provenance & Evidence