反应详情

Reaction of phenylacetylene (0.04 g, 0.32 mmol) and 157d (0.10 g, 0.32 mmol) within 4 h as described for synthesis of 158a gave compound 158d (0.092 g, 72%) as a white solid. 1H NMR (400 MHz, CDCl3) δ 7.78 (m, 3H), 7.30 (m, 8H), 6.79 (d, J=6.8 Hz, 1H), 6.57 (d, J=7.3 Hz, 1H), 5.94 (t, J=7.1 Hz, 1H), 5.02 (s, 2H), 4.31 (t, J=7.0 Hz, 2H), 3.87 (t, J=7.2 Hz, 2H), 1.91 (m, 2H), 1.74 (m, 2H), 1.30 (m, 2H). 13C NMR (100 MHz, CDCl3) δ 157.80, 148.57, 147.39, 136.02, 130.44, 128.64, 128.56, 128.27, 127.81, 127.71, 127.05, 125.40, 119.57, 115.12, 104.49, 70.40, 49.71, 49.06, 29.42, 28.03, 23.05.