Ethyl(4,7-dimethoxy-6-azaindol-3-yl)-oxoacetate → Potassium (4,7-dimethoxy-6-azaindol-3-yl)-oxoacetate

HRID 539841Notes

Reaction equation

HRID 539841 reaction equation
N1C2C(=CC=CN=2)C(C(=O)C([O-])=O)=C1.[K+:15].[CH3:16][O:17][C:18]1[CH:26]=[N:25][C:24]([O:27][CH3:28])=[C:23]2[C:19]=1[C:20]([C:29](=[O:35])[C:30]([O:32]CC)=[O:31])=[CH:21][NH:22]2>>[CH3:16][O:17][C:18]1[CH:26]=[N:25][C:24]([O:27][CH3:28])=[C:23]2[C:19]=1[C:20]([C:29](=[O:35])[C:30]([O-:32])=[O:31])=[CH:21][NH:22]2.[K+:15]

Participants

3

Reactant 2

HCID 22893828Ethyl(4,7-dimethoxy-6-azaindol-3-yl)-oxoacetateHCID 23721194Alfa-oxo-1H-pyrrolo-[2,3B]pyridine-3-acetic acid monopotassium salt

Product 1

HCID 22893810Potassium (4,7-dimethoxy-6-azaindol-3-yl)-oxoacetate

Procedure

Compound 3ao (Potassium (4,7-dimethoxy-6-azaindol-3-yl)-oxoacetate) was prepared (as a yellow solid), by the same method used to prepare compound 3a except Ethyl (4,7-dimethoxy-6-azaindol-3-yl)-oxoacetate was employed as the starting material. MS m/z: (M+H)+ of the corresponding acid of compound 3ao (M−K+H)+ calcd for C11H11N2O5: 251.07; found 251.09. HPLC retention time: 0.69 minutes (column B).

Sources & evidence

ORD record
ord-162474a13dbd46c1b7124b9c4de9260c
Source dataset
uspto-grants-2014_10
Patent number
US08871771B2

Reaction notes

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